Drug Utilization Pattern in Chronic Kidney Disease Associated Comorbidities at a Tertiary Care Hospital

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Drug Utilization Pattern in Chronic Kidney Disease Associated Comorbidities at a Tertiary Care Hospital
J Young Pharm. Vol 15/Issue 4/2023 
Harshita H1, Neha Thakur1, Jasmine Yadav1, Monika M1, Shreya Gupta1 and Inderjeet Verma1
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1M.M. College of Pharmacy, Maharishi Markandeshwar (Deemed to be University), Mullana Ambala, Haryana, INDIA

Corresponding author.

Correspondence: Dr. Inderjeet Verma Professor, M.M. College of Pharmacy, Maharishi Markandeshwar (Deemed to be University), Mullana, Ambala-133207, Haryana, INDIA. Email: indupup@gmail.com
Received August 08, 2023; Revised September 10, 2023; Accepted September 27, 2023.
Copyright 2023 Authors
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Citation

1.Harshita H H, Thakur N, Yadav J, Monika M M, Gupta S, Verma I. Drug Utilization Pattern in Chronic Kidney Disease Associated Comorbidities at a Tertiary Care Hospital. Journal of Young Pharmacists [Internet]. 2023 Dec 22;15(4):743–7. Available from: http://dx.doi.org/10.5530/jyp.2023.15.102
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Published in: Journal of Young Pharmacists,2203; 15(4): 743-747. Published online: 07 December 2023DOI: 10.5530/jyp.2023.15.102

ABSTRACT

Background

Patients with Chronic Kidney Disease (CKD) with multiple Comorbidities like Hypertension, Diabetes, and Anemia require Numerous Drugs. Multiple drugs Predispose to Potential drug-drug Interactions, which increase hospital stay, health care expenses, and ultimately morbidity and mortality. So, we aim to study the drug utilization pattern in CKD-associated comorbidities at a tertiary care hospital.

Materials and Methods

A HospitalBased Observational and Cross-Sectional study was conducted among patients with CKD-associated comorbidities enrolling IPD, OPD, and medicine ward patients for one year. The data collection form noted details like Socio-Demographic and clinical characteristics, past medication history, Comorbidities, and current medications. Drugs were categorized according to the Food and Drug Administration (FDA) and rationality score per the World Health Organization (WHO).

Results

A total of 100 patients were analyzed. The mean age of the patients was 55.8, out of which 69% as male maximum patients belong to stage 5 72%. Hypertension was the most prevalent comorbidity followed by diabetes and calcium channel blockers (33.3%), insulin (soluble) 33.8% and erythropoietin (51%) were the most frequently prescribed drugs for the treatment of hypertension, diabetes, and Anemia, respectively. Mainly prescribed antibiotics belong to the Beta-Lactamase (26.6%) Penicillin Class.

Conclusion

This study’s results showed that CKD was more prevalent in males and that the highest number of patients had end-stage renal disease. CKD patients are concomitantly affected by hypertension, diabetes, CVD, and Anemia. Calcium channel blockers, Insulin, and Erythropoietin were the most frequently prescribed drugs.

Keywords: Drug utilization pattern, Chronic Kidney Disease, Hypertension, Diabetes, Anemia, Comorbidities