A Rare Scenario: A Female Child with Bladder Exstrophy and Complications

1Department of Pharmacy Practice, Parul Institute of Pharmacy, Parul University, Limda, Vadodara, Gujarat, INDIA

Corresponding author.

Correspondence: Ms. Akshi Prajapati Department of Pharmacy Practice, Parul Institute of Pharmacy, Parul University, Limda, Vadodara -391760, Gujarat, INDIA. Email: akshiprajapati858@gmail.com
Received December 12, 2023; Revised January 05, 2024; Accepted January 12, 2024.
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Citation

1.Prajapati A, Shah A, Shah C, Gandhi R, Suratiya N. A Rare Scenario: A Female Child with Bladder Exstrophy and Complications. Journal of Young Pharmacists [Internet]. 2024 Feb 15;16(1):134–6. Available from: http://dx.doi.org/10.5530/jyp.2024.16.18
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Published in: Journal of Young Pharmacists, 2024; 16(1): 134-136. Published online: 07 July 2025DOI: 10.5530/jyp.2024.16.18

ABSTRACT

Bladder Exstrophy is an anomaly that is uncommon from birth and influences various aspects of the urinary tract, genitals, pelvis, and anus. The defining characteristic of this condition is the abnormal development of the bladder outside the fetal body. Clinical signs in affected individuals often include the bladder being exposed from the abdomen, a flattened puborectalis sling, separation of the pubic symphysis, and ulcers in the bladder mucosa, urine dribbling, and skin excoriation. The primary treatment for bladder exstrophy typically involves surgery, tailored to the severity of the condition. In one case, a female child was passing urine through her navel instead of the urethra. Following a confirmed diagnosis, a single-stage repair was recommended for the exstrophied bladder. However, before a scheduled follow-up appointment, the patient’s stitches ruptured, resulting in urine leakage from the operated site and pus discharge from the urethra. Based on the patient’s complaints and laboratory results, a diagnosis of acute kidney injury and urinary tract infection in the context of bladder exstrophy was established, leading to the plan for a resuturing surgery. It’s important to note that the risk of bladder exstrophy is increased when the mother is exposed to smoking and radiation during the first trimester of pregnancy. Bladder exstrophy in a female child is a rare and complex congenital condition that necessitates a multidisciplinary approach for diagnosis, management, and long-term care.
Keywords: Epispadias, Cloacal exstrophy (OEIS Syndrome), Hydronephrosis, Urinary Tract Infection (UTI), Acute Renal Failure (ARF), Severe Cystitis