A Comprehensive Overview of Edible Natural Excipients and their Potential Use in Pharmaceutical Formulation Development

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A Comprehensive Overview of Edible Natural Excipients and their Potential Use in Pharmaceutical Formulation Development
J Young Pharm. Vol 15/Issue 4/2023 Review Article 
Jahnabi Sarmah 1, Ananta Choudhury1, Himangshu Deka1, Debgopal Ganguly2, Dhiraj Baishya1 and Rosamund Jyrwa3
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1Faculty of Pharmaceutical Science, Assam Down Town University, Panikhaiti, Guwahati, Assam, INDIA

2NSMS Institute of Pharmacy, Nachan Road, Kamalpur, Durgapur, Paschim Bardhaman, West Bengal, INDIA

3Pratiksha Institute of Pharmaceutical Sciences, Chandrapur Rd, Near Central Training Center, Panikhaiti, Barchapari, Assam, INDIA

Corresponding author.

Correspondence: Dr. Ananta Choudhury Faculty of Pharmaceutical Science, Assam Down Town University, Sankar Madhab Path Gandhi Nagar, Panikhaiti, Guwahati-781026, Assam, INDIA. Email: anantachoudhury@gmail.com
Received May 22, 2023; Revised July 01, 2023; Accepted July 22, 2023.
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Citation

1.Sarmah J, Choudhury A, Deka H, Ganguly D, Baishya D, Jyrwa R. A Comprehensive Overview of Edible Natural Excipients and their Potential Use in Pharmaceutical Formulation Development. Journal of Young Pharmacists [Internet]. 2023 Dec 22;15(4):589–94. Available from: http://dx.doi.org/10.5530/jyp.2023.15.83
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Published in: Journal of Young Pharmacists, 2023; 15(4): 589-594. Published online: December 07, 2023 DOI: 10.5530/jyp.2023.15.83

ABSTRACT

This review aims to explore the prospective scope of excipients obtained from edible natural sources and its unique application in the field of pharmaceutical formulation development. A systematic literature search was conducted using data base like PubMed, Science Direct, Embase, and Google Scholar. A total of 50 articles were identified and reviewed, which primarily focused on the unique application of edible natural sources as excipients in the field of pharmaceutical formulation development. The results revealed that edible natural sources like Dillenia indica, Abelmoschus esculentus; Oryza sativa L; Artocarpus heterophyllus; Tamarindus indica; Musa paradisiaca; Mangifera indica; Ipomoea batatas; Hibiscus sabdariffa and Solanum tuberosum are a promising source of excipients and have great potential to be used in the formulation of pharmaceutical dosage form. Furthermore, the use of these sources may potentially reduce the costs associated with the production of pharmaceuticals dosage form and could also improve the safety profile of the drugs. The review highlights the importance of the use of edible natural sources as excipients and their potential to revolutionize the field of pharmaceutical formulation development.

Keywords: Edible natural substance, Excipients, Diluents, Natural binders, Pharmaceutical formulation